NAD+ precursors and the longevity stack
What NMN, NR and niacinamide actually do in the mitochondrion — and why the dose, not the molecule, is where most stacks fail.
NAD+ is the redox currency every mitochondrion spends to convert food into ATP. By the fifth decade it has roughly halved, and the visible consequences — slower recovery, slower cognition, slower repair — are downstream of that single bookkeeping problem.
Why precursors, not NAD+ itself
Oral NAD+ does not survive the gut intact. The body builds it from precursors: nicotinamide riboside (NR), nicotinamide mononucleotide (NMN), and the older niacinamide. Each enters the salvage pathway at a different rung; each has a different cost profile.
The molecule is the headline; the gram-per-serving is the science.
What we put in H-1
H-1 carries pharmacological-grade niacinamide alongside ribose and a methyl-donor matrix (betaine, glycine, B-complex) so the salvage pathway has its raw material and the methylation it costs to run. Disclosed by the milligram on every pouch.